About ValeasO2

A microbiome science company redefining how the body manages oxygen.

Founded on decades of probiotic research, ValeasO2 develops precision formulations designed to improve oxygen allocation under stress conditions.

Who We are

ValeasO2 is a microbiome science company focused on systemic oxygen efficiency.

Founded by Prof. Claudio De Simone — inventor of the De Simone Formulation and pioneer in high-potency, clinically documented probiotic research — ValeasO2 builds upon decades of innovation to explore a new frontier in physiology: how the body allocates and utilizes oxygen under stress.

Rather than increasing oxygen delivery or airflow, ValeasO2 is designed to support how oxygen is managed within the body — improving efficiency where demand exceeds availability.

Our Approach

Positioning

Unlike traditional approaches that increase oxygen supply, ValeasO2 targets oxygen demand at the gut level — where a significant portion of systemic oxygen consumption occurs.

Mechanism

Through a patented, gut-mediated oxygen-sparing pathway, the formulation reduces intestinal oxygen consumption, supporting redistribution to metabolically active tissues.

Impact

Supporting systemic oxygen efficiency during exertion, altitude exposure, oxygen-limited environments, recovery, and aging.

Our Mission

To redefine oxygen physiology through microbiome science — improving resilience in conditions where oxygen demand exceeds supply.

Our Platform

ValeasO2 is developing a microbiome-based platform with applications spanning performance, altitude physiology, respiratory health, metabolic disease, and neurodegeneration.